Phenylephrine reddit

Evidence of phenylephrine's effectiveness comes from a review that combined and analyzed the results of seven individual studies. It found the drug had a small but real effect on nasal airway ...

In Boards and Beyond video on autonomic nervous system drugs, Dr Ryan tells that the primary determinant for systolic blood pressure is the cardiac output. Phenylephrine is an alpha 1 agonist and would increase the TPR and diastolic pressure (which makes perfect sense). However, the diagram regarding drug effects on blood pressure for ...Phenylephrine is an over-the-counter nasal decongestant available in 5 mg and 10 mg tablets, as well as an oral solution. It is also available in an injectable form which is only used in an inpatient setting by medical professionals for low blood pressure. Phenylephrine can be purchased without restriction or logging of the purchaser’s ...2. Mengatasi hipotensi. Dewasa (ringan/sedang): sebagai larutan 1%, berikan 2–5 mg lewat suntikan subkutan (SC) atau intramuskular (IM), yang dapat dilanjutkan 1–10 mg sekitar 15 menit setelah dosis pertama; sebagai alternatif, 100–500 mcg larutan 1% diberikan lewat suntikan intravena (IV) lambat yang bisa diulang setiap 15 …Phenylephrine is a decongestant and works by constricting blood vessels (although it’s not very good at this). I can’t imagine it exacerbating RLS because it doesn’t enter the CNS at all and it’s also just kind of a useless systemic drug in general. That doesn’t mean it couldn’t make your RLS worse by acting locally on the blood ...Norepinephrine does have a little bit of beta activity, so it can in theory increase HR slightly. The predominant alpha activity causes vasoconstriction, which results in a rise in blood pressure, which will trigger baroreceptors, which will lower the heart rate. In practice, the low beta activity is usually far outweighed by the effect on the ...I agree with you. In pretty much every situation a human would consume aspartame, it is totally and completely harmless. There have been studies that showed problems, but they require such insane doses of aspartame in such a short period of time that they're ridiculous.A warning about stimulants and cold medicine. In a nutshell, I was on 10 of Prozac titrating up to 20 slowly, and had just increased my dose of Vyvanse again when my asthma flaired up. I had to take my Albuterol inhaler and Robitussin with dextromethorphan and guaifenesin. I had a nightmare response that caused a crazy panic episode that lasted ...Significantly more effective as a decongestant than phenylephrine. May be used in addition to pain relievers, antihistamines, cough suppressants, expectorants, or antibiotics. Some manufacturers have reformulated cough and cold preparations to contain phenylephrine rather than pseudoephedrine. Extended-release tablets may be administered once ...

/r/Breadtube is becoming a place for the perpetuation of YouTube drama, not "going against the prevailing winds of the internet". Let's get it back on track and post work by artists who are pushing in new directions.Brompheniramine And Phenylephrine (Rynex PE) received an overall rating of 0 out of 10 stars from 0 reviews. See what others have said about Brompheniramine And Phenylephrine (Rynex PE), including the effectiveness, ease of use and side eff...Agreed. Currently I am in pharmacy school. All the literature points to that it is either ineffective or the dosing is not right. Regardless, replacing pseduoephedrine with phenylephrine has not curbed methamphetamine production. False product extentions are confusing patients.The phenylephrine (PE) form is no better than a placebo when taken in pill form. It only works as a decongestant when used in a liquid form on direct contact with nasal tissues. I still can't believe they actually approved the PE forms of decongestant pills.Depending if it’s a dry cough or productive. Productive I’ll recommend one thats only guaifenesin and tell them they really need to take it with at least 8oz of water to thin the mucus so they can cough it up. I don’t like combination OTC. Sometimes it’s just over kill. If it’s a dry cough then I’ll skip Mucinex cause I’m looking ...Phenylephrine is a direct-acting sympathomimetic amine chemically related to adrenaline and ephedrine with potent vasoconstrictor property. Phenylephrine is a post-synaptic alpha-adrenergic receptor agonist that causes vasoconstriction, increases systolic/diastolic pressures, reflex bradycardia, and stroke output. Reply.It really just depends for everyone if it will give you bad side effects or not. Since you have a low tolerance to adderall, take 5mg first and see how bad the load is. If it isn't too bad, you can take more, but know that the half life of phenylephrine is about 3 hours, so it does not go away quickly. willis81808 • 9 yr. ago.

TIL that Phenylephrine, the nasal decongestant that replaced pseudoephedrine in OTC cold medicine, was shown to be ineffective vs placebo at up to 4X the recommended …Don’t mix combo meds containing Sudafed and alcohol. It is also important to recognize that the active ingredient in Sudafed is often found in combination drugs used to treat cold and/or flu symptoms. These drugs typically contain medications that do have known drug-drug or drug-alcohol interactions, such as Tylenol, Advil, or Benadryl.The phenylephrine should be avoided. You can of course perform an extraction. But the easiest solution would be to save that syrup for a rainy day when you …A website’s welcome message should describe what the website offers its visitors. For example, “Reddit’s stories are created by its users.” The welcome message can be either a statement of purpose or brief extracts from the most-important p...Well, phenylephrine is metabolized by MAO, so going with a much lower dose would be a good idea if you did take it. There are reports in the literature of patients taking selegiline and amphetamine, combined with a beta-blocker for hypertensive side effects. Granted that's a selective MAOI, but combining MAOIs and stimulants isn't an automatic ...

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Phenylephrine is used in a broad array of over-the-counter medications like Sudafed PE and Dimetapp. The drug brought in nearly $1.8 billion in sales in 2022, according to an FDA briefing document ...Dilated blood vessels can cause nasal congestion (stuffy nose). Pseudoephedrine is used to treat nasal and sinus congestion, or congestion of the tubes that drain fluid from your inner ears, called the eustachian (yoo-STAY-shun) tubes. Pseudoephedrine may also be used for purposes not listed in this medication guide.Depending if it’s a dry cough or productive. Productive I’ll recommend one thats only guaifenesin and tell them they really need to take it with at least 8oz of water to thin the mucus so they can cough it up. I don’t like combination OTC. Sometimes it’s just over kill. If it’s a dry cough then I’ll skip Mucinex cause I’m looking ... Yes, phenylephrine is great for draining the mucous from hemorrhoids. adenocard • 1 yr. ago. It’s a bit counterintuitive because most of us are used to thinking of vessel constriction as a process that increases pressure. Like epinephrine increases blood pressure though vasoconstriction.The most important difference between phenylephrine (PE) and pseudoephedrine (PDE) is that the efficacy as PE as a decongestant is unproven, whereas there is some evidence that oral PDE is effective. The main reasons for a lack of effectiveness of PE include: Although both PE and PDE are well absorbed from the gut, PE is extensively metabolized ...

MAOIs are amazing antidepressants and anti-anxiety agents - in part because they work very differently compared to most other neuropharmaceuticals. MAOIs work intracellularly and compared to other ADs there is tolerance/counterregulation to that, hence much less "poop-out". However, there is a reason why MAOIs are underprescribed.I have a few theories that may explain why: The drug would exist already in solution, which might make it easier to separate from inactive ingredients. This would benefit those attempting to produce methamphetamine. The drug itself may damage parts of the nose. It may simply not be very bioavailable intranasally. Then, draw off the top (ether) layer with the eyedropper, and throw away the lower (water) and cloudy layer. Place the ether in the marked container. Repeat this until you have about 1.5 oz. of ether. Put the cap on it, and put it in the freezer if you can. Rinse the other bottle and let it stand.In fact, some research has found that at the current recommended doses of phenylephrine it offers minimal symptom improvement. It may be safer for people with high blood pressure and heart disease, but there is not enough research to be certain. Decongestant effects beyond the noseDepending if it’s a dry cough or productive. Productive I’ll recommend one thats only guaifenesin and tell them they really need to take it with at least 8oz of water to thin the mucus so they can cough it up. I don’t like combination OTC. Sometimes it’s just over kill. If it’s a dry cough then I’ll skip Mucinex cause I’m looking ... Aug 17, 2023 · The most important difference between phenylephrine (PE) and pseudoephedrine (PDE) is that the efficacy as PE as a decongestant is unproven, whereas there is some evidence that oral PDE is effective. The main reasons for a lack of effectiveness of PE include: Although both PE and PDE are well absorbed from the gut, PE is extensively metabolized ... Phenylephrine. Phenylephrine is a widely used vasopressor in the operating room for the treatment of hypotension. The primary binding target of phenylephrine is the α-adrenergic receptor with the highest affinity for the α1 -receptor. Phenylephrine is an α 1 selective agonist but may affect β-receptors in high doses.Super interesting article thanks! Epipens stored in EMS vehicles between 1-11 years past expiration only contained up to 31% of original potency. While epipens tested with normal storage up to 90 months past expiration date decreased proportionally with age. Makes me much more careful with epipens -- that's for damn sure!Lock the medicine up high, out of sight and reach of young children. If you think a child has swallowed too much cough or cold medicine, use the web POISON CONTROL ® online tool for guidance or call Poison Control at 1-800-222-1222. Rose Ann Gould Soloway, RN, BSN, MSEd, DABAT emerita. Clinical Toxicologist.Then, draw off the top (ether) layer with the eyedropper, and throw away the lower (water) and cloudy layer. Place the ether in the marked container. Repeat this until you have about 1.5 oz. of ether. Put the cap on it, and put it in the freezer if you can. Rinse the other bottle and let it stand.This page says: When you bring your personal medicines into Japan up to the amount described below, you do not have to apply for "Yunyu Kakunin-sho", instead the officers at customs check the amount of your bringing medicines, and then you can bring them into Japan. Poison, Deadly poison, Prescription drug : Up to 1 month supply.

When Sudafed (the OG Sudafed with pseudoephedrine) was taken off of the regular OTC shelves and moved behind the pharmacy counter Sudafed PE (the one that’s just phenylephrine) was used to fill the empty space on the store shelves and less savvy consumer bought it, thinking “Sudafed is sudafed” … and phenylephrine IS an effective ...

19 fév. 2010 ... Pseudoephedrine is found in Sudafed, as well as many combination products. Phenylephrine is the only other oral nasal decongestant known to be ...The fast-acting Pseudoephedrine HCI formula is both powerful and community conscious, so you can feel better about feeling better. Tarex® meth-blocking technology protects over 98% of the medicine in this maximum-strength nasal decongestant from being illegally converted to meth by today's illicit methods.”. 11K.According to Healthline, the phenylephrine in Preparation H “may temporarily make the area around the eyes appear tighter.”. However, applying the cream around the eye area can have unwanted side effects. According to the Mayo Clinic, hydrocortisone can cause a “thinning, weakness, or wasting away of the skin.”.TIL that Phenylephrine, the nasal decongestant that replaced pseudoephedrine in OTC cold medicine, was shown to be ineffective vs placebo at up to 4X the recommended dose, and was not well tolerated starting at 4X the recommended dose. : r/todayilearned by teefourApr 21, 2023 · Takeaway. Pseudoephedrine and phenylephrine are both nasal decongestants but can have different side effects. You can only purchase pseudoephedrine from pharmacy staff and have to show your ID ... Like super fast heart rate, shaky, sweaty,anxiety, kinda dizzy. Feels like I did a fat line of bad coke. I am not a rookie or a light weight and I take actual stimulants often. I just had no idea a decongestant could make me feel like this. Is that normal?USA TODAY A Food and Drug Administration-assembled board of advisers has determined that the most popular decongestant ingredient on the market is not actually effective in treating nasal...When Sudafed (the OG Sudafed with pseudoephedrine) was taken off of the regular OTC shelves and moved behind the pharmacy counter Sudafed PE (the one that’s just phenylephrine) was used to fill the empty space on the store shelves and less savvy consumer bought it, thinking “Sudafed is sudafed” … and phenylephrine IS an effective ... tripped on this dose years ago, im not sure if it was the phenylephrine but it has extreme physical euphoria and delirious hallucinations in the dark, would lapse in and out of dreams and see them fading into the cieling. i specifically remember seeing a pink whale on the cieling

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Phenylephrine comes as a 0.125%, 0.25%, 0.5%, and 1% solution (liquid) to spray into the nose. It is usually used as needed, not more than every 4 hours. The 0.5% and 1% solutions may be used in adults and children 12 years of age and older. The 0.25% solution may be used in children 6 to 12 years of age.Phenylephrine : r/depression • 12 yr. ago by coolgherm Phenylephrine Does anybody know about using phenylephrine as an antidepressant. I have had a cold for the last two weeks and have been taking dayquil to combat the mucus. It has phenylephrine in it. For the last few days of taking it, I have felt better than I have in years.Medicated decongestant spray like Afrin works pretty well if you use it correctly. Give each nostral a nice coating (1 or 2 pumps) every twelve hours and it won't lose its effectiveness until after 4 or 5 days.The phenylephrine should be avoided. You can of course perform an extraction. But the easiest solution would be to save that syrup for a rainy day when you …Concerta is a prescription drug used for ADHD. Find out about possible interactions with alcohol, other drugs, supplements, foods, and more.I personally think phenylephrine is a placebo. So many people don't know any better and just keep taking Sudafed because "that's what you take" and don't even think to look at that. But it's literally never done anything for me.Currently about 5 weeks in on 10 mg. I got a sinus infection, was wondering if anybody knows good cold medicine that's safe to take. Specifically I have tylenol sinus and headache which has Phenylephrine HCI in it. A brief search I couldn't find anything about interactions but figured I would see if anybody here had some info. First step is to remove the top part (may need to be pried off, the seam is pretty tight and hard to see), and then empty the bottle of the saline. Next, you'll need to crush up and add your coke to the bottle. I use one gram of high quality cocaine per bottle, but you could make it less or more potent.Pseudoephedrine is an adrenergic receptor ligand, but it has far less stimulating properties than methamphetamine and a better pharmacological profile than ephedrine. It is famous for drying nasal passages during colds and allergies, at which it excels. Some people still notice amphetamine-like effects of sleeplessness and jitters at those ... ….

Phenylephrine is a decongestant used to relieve nasal pressure and stuffiness often associated with a cold or allergies. It supposedly works by stimulating …Paracetamol also helps reduce fever . Phenylephrine Hydrochloride 5mg. Phenylephrine helps to relieve blocked and runny noses. Each Night Tablet contains ...Phenylephrine nasal spray has the same 3 day use limit; and oral phenylephrine is trash. I would never recommend it. If symptoms persist beyond 3 days I’d recommend seeing a physician anyway; but they can have some pseudoephedrine in the mean time. But honestly; I’m pretty sure rebound congestion from oxymetazoline is a myth.Sep 13, 2023 · The federal purchase limit is 3.6 milligrams of pseudoephedrine base in a single day and nine milligrams in a single month. The monthly limit should be enough to keep you covered during allergy ... Depending if it’s a dry cough or productive. Productive I’ll recommend one thats only guaifenesin and tell them they really need to take it with at least 8oz of water to thin the mucus so they can cough it up. I don’t like combination OTC. Sometimes it’s just over kill. If it’s a dry cough then I’ll skip Mucinex cause I’m looking ...Sudafed is a stimulant As a stimulant medication, Sudafed can mask that tipsy feeling that sometimes occurs after a drink or two. And masking inebriation is a great way to wind up hungover (on a side note, if you do find yourself hungover for this reason or some other, here are a few things you can do to alleviate symptoms). “Sudafed can …Even 120 mg, twice the medical dose, has significant nice effects. There is a mood lift with a greater appreciation of the present, due to I guess an improved ability to focus on the present. My body feels light and movement feels easier. Higher doses make the mood lift even more impressive, but also become rushy.Sex m Age 23 Hight 6'4 Weight 105kg. So I've taken a high dose of phenylephrine hydrochloride in a bottle of cough syrup. Was wondering what could be some of the side effects of taking such a high dose of phenylephrine hydrochloride? Phenylephrine reddit, [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1]