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Malignant melanoma may arise from melanocytes found on the skin or rarely from mucosal surfaces, under the nails and in the meninges. Melanoma may arise from common acquired naevi or from dysplastic naevi. They may also arise from the solar lentigo or atypical lentigo. Most arise de novo. The dermoscopic features are enormously variable.

Granuloma annulare may be a delayed hypersensitivity reaction to a component of the dermis or a reaction pattern to numerous triggers. Reported triggering events have included many skin infections and infestations, and types of skin trauma. Inflammation is mediated by tumour necrosis factor alpha ( TNF α). The reason this occurs is unknown. Carotenoderma is due to carotenaemia. Primary carotenaemia is usually due to excessive intake of carotenoid-containing foods or supplements. Carotene is found in all pigmented fruits and vegetables. High levels are associated with a deep yellow, orange, or green colour. Examples of fruit and vegetables with a high β-carotene content include ...Dermatomyositis is thought to be caused by a microangiopathy affecting skin and muscle. There is a genetic predisposition to the development of dermatomyositis such as the PTPN22 gene and HLA associations identified include: Anti-Mi-2 antibodies: HLA DRB1*07 and DQA*0201. Silica exposure — in tradespeople. DermNet is a not-for-profit, independent health publishing organisation with a mission to make authoritative information about the skin accessible to anyone in the world. We have information about almost every skin condition and have a library of over 20,000 dermatology images. All of our content is created or reviewed by a dermatologist and we ... Authoritative facts about the skin from DermNet New Zealand. DermNet provides Google Translate, a free machine translation service. Note that this may not provide an exact translation in all languages. Topics A-Z. Images. Cases. Jobs. AI dataset. More . Skin checker; About; Browse ... The Australian and New Zealand Melanoma …Photodynamic therapy (PDT) is a treatment used mainly for superficial types of skin cancer. PDT is effective in treating actinic keratoses, in situ squamous cell carcinoma (Bowen disease), and superficial basal cell carcinomas. It may also be used for treatment of small, thin, low-risk nodular basal cell carcinomas outside of the head and neck ...Aphthous ulceration is classified into three types. Recurrent minor aphthous ulcer (80%). This is less than 5 mm in diameter and heals within 1–2 weeks. Major aphthous ulcer, which is large (often more than 10 mm) and takes weeks or months to heal and leaves a scar. Herpetiform ulcers, which are multiple pinpoint ulcers that heal within a month.Scalp psoriasis is a skin condition characterised by red, thickened, well- demarcated patches or plaques with overlying silvery-white scales, affecting part or all of the scalp. It can be contained within the hairline, though frequently affects the back of the head, or extends onto the forehead ( facial psoriasis ), ears, or neck.

A list of the most commonly used key terms and phrases in dermatology.Decreased arterial flow. The blockage or narrowing of arteries by the small clots that lead to blue toe syndrome can result from a number of different conditions.. Embolisation. Cholesterol emboli are cholesterol fragments or fibrin – platelet material released into the bloodstream from ulcerated arteriosclerotic plaques in the large arteries (eg, the aorta, … Guttate psoriasis is a clinical diagnosis, aided by dermoscopy, which can be confirmed on skin biopsy. Examination and investigations should include a search for streptococcal infection. Tests may include: Swabs for bacteriology. Blood tests — Anti-streptolysin O titre (ASOT), anti-DNase B titre. Ramsay Hunt syndrome is a rare peripheral facial neuropathy. It is a type of shingles due to reactivation of the varicella zoster virus (VZV) in the geniculate ganglion of cranial nerve VII, which supplies the facial nerve. Ramsay Hunt syndrome is characterised by unilateral facial weakness and painful blisters — either in the ear canal on ...DermNet NZ revision August 2021. Table of contents. Introduction Demographics Causes Clinical features Diagnosis Treatment Outlook. What is pityriasis versicolor? Pityriasis …A solitary cutaneous neurofibroma is a common nerve -sheath tumour. It presents as a skin-coloured, soft-to-firm papule or nodule with a smooth surface. Characteristically, pressing on the lesion with a finger causes it to fold in so that the outer surface becomes an inner one, a manoeuvre called "buttonhole invagination".

Ramsay Hunt syndrome is a rare peripheral facial neuropathy. It is a type of shingles due to reactivation of the varicella zoster virus (VZV) in the geniculate ganglion of cranial nerve VII, which supplies the facial nerve. Ramsay Hunt syndrome is characterised by unilateral facial weakness and painful blisters — either in the ear canal on ...Tofacitinib (Xeljanz, Xeljanz XR ®, US) is an oral small- molecule inhibitor of Janus kinase (JAK) 1 and 3 that is used to treat psoriatic arthritis, rheumatoid arthriti s, inflammatory bowel disease, and ankylosing spondylitis. JAK enzymes respond to extracellular growth factors, and cytokines which activate signal transduction and cell ...Keratosis pilaris is a very common, dry skin condition caused by keratin accumulation in the hair follicles. The Latin term keratosis means ‘ scaly skin’, and pilaris means ‘hair’. Keratosis pilaris usually starts in …Keratoacanthoma (KA) is a common, rapidly growing, locally destructive skin tumour . KAs may regress spontaneously with scarring, but clinically they may be indistinguishable from well- differentiated squamous cell carcinoma (SCC) and the clinical course may be unpredictable. Thus, many clinicians and pathologists prefer the term SCC, KA-type ... It is characterised by: Open and closed uninflamed comedones (blackheads and whiteheads) Inflamed papules and pustules. In severe acne, nodules and pseudocysts. Post-inflammatory erythematous or pigmented macules and scars. Adverse social and psychological effects. Severity is classified as mild, moderate, or severe.

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Folliculitis means an inflamed hair follicle due to any cause. The result is a tender red spot, often with a surface pustule. Folliculitis may be superficial or deep. It can affect anywhere there are hairs, including chest, back, buttocks, arms, and legs. Acne and its variants are also types of folliculitis.DermNet NZ is a comprehensive online resource for skin health information. Learn about psoriasis, a chronic inflammatory skin condition with red and scaly plaques, its types, causes, diagnosis and treatment options. Lichen planus is a chronic inflammatory condition affecting the skin and mucosal surfaces. Learn about its symptoms, causes, diagnosis, treatment, and complications with images and references from DermNet NZ, a comprehensive online resource for skin health. It affects the superficial layers of the epidermis and is typically caused by Staphylococcus aureus and Streptococcus pyogenes (Group A beta – haemolytic streptococci (GABHS)). It can be classified into non- bullous (also known as ‘school sores’) and bullous impetigo. Ecthyma is a deep form of impetigo causing deeper erosions of the skin ...

Treatment of seborrhoeic dermatitis often involves several of the following options. Keratolytics : used to remove scale when necessary, e.g. salicylic acid, lactic acid, urea, propylene glycol. Topical antifungal agents: applied to reduce Malassezia e.g. ketoconazole, or ciclopirox shampoo and/or cream. Tinea versicolor is more accurately called pityriasis versicolor. This is a common yeast infection on the trunk. Tinea incognito refers to a tinea infection in which the clinical appearance has changed because of inappropriate treatment. Tinea nigra is a mould infection (not a dermatophyte). It affects the palms or soles, which appear brown (on ...Ramsay Hunt syndrome is a rare peripheral facial neuropathy. It is a type of shingles due to reactivation of the varicella zoster virus (VZV) in the geniculate ganglion of cranial nerve VII, which supplies the facial nerve. Ramsay Hunt syndrome is characterised by unilateral facial weakness and painful blisters — either in the ear canal on ...DermNet is a not-for-profit, independent health publishing organisation with a mission to make authoritative information about the skin accessible to anyone in the world. We have information about almost every skin condition and have a library of over 20,000 dermatology images. All of our content is created or reviewed by a dermatologist and we ...Cherry angioma is an asymptomatic firm red, blue, or purple papule, 0.1–1 cm in diameter. When thrombosed, it can appear black in colour until examined with a dermatoscope when the red or purple colour is more easily seen. Cherry angiomas are usually multiple. They are usually scattered over any part of the body surface, but are rarely found ...Aug 24, 2021 · Bimekizumab (Bimzelx®) is a novel humanised immunoglobulin (IgG1) monoclonal antibody used to treat moderate to severe plaque psoriasis, generalised pustular psoriasis, and psoriatic erythroderma. Bimekizumab selectively and directly inhibits interleukin 17A and 17F (IL-17A and IL-17F). It is produced in a genetically engineered Chinese ... Itchy anus is a common complaint described as an intense itch in the perianal area between the buttocks. Perianal itch can be the result of an infestation, skin infection, inflammatory skin condition, and, rarely, a skin tumour. When there is no obvious cause for the itch it is called pruritus ani.Urticaria pigmentosa. Urticaria pigmentosa is a form of cutaneous mastocytosis in which there are brown macules and papules. Urticaria pigmentosa is mostly seen in infants and improves with age. It may also arise in adults when it tends to persist. Lesions may affect trunk and limbs, and less often scalp and face.Curettage. The lesion should be sent to a pathology laboratory for analysis. The wound surface is then cauterised with a hot wire beaded tip or electrosurgical unit (diathermy). This stops bleeding and helps destroys any remaining skin tumour cells. This procedure is usually repeated twice for malignant skin lesions (serial curettage and cautery).Malignant melanoma may arise from melanocytes found on the skin or rarely from mucosal surfaces, under the nails and in the meninges. Melanoma may arise from common acquired naevi or from dysplastic naevi. They may also arise from the solar lentigo or atypical lentigo. Most arise de novo. The dermoscopic features are enormously variable.

Basal cell carcinoma (BCC) is a common, locally invasive, keratinocytic, or nonmelanoma skin cancer. It is also known as rodent ulcer and basalioma. Patients with BCC often develop multiple primary tumours over time. Basal cell carcinoma can be pigmented or nonpigmented. Its subtypes include: Other less common variants.

Infection of internal organs, including the gastrointestinal tract, lungs, and brain ( encephalitis) Herpes zoster is infectious to people who have not previously had chickenpox. Herpes zoster in the early months of pregnancy can harm the fetus, but luckily this is rare. Shingles in late pregnancy can cause chickenpox in the fetus or newborn.Skin conditions caused or aggravated by infection by malassezia include: Pityriasis versicolor – most often due to M. globosa, M. sympodialis and M. furfur. Malassezia folliculitis due to the yeast growing in the hair follicles where they produce inflammation. Steroid acne. Seborrhoeic dermatitis, dandruff, sebopsoriasis and facial or scalp ...Trichotillomania is estimated to affect up to 4% of the general population. It can affect males and females of any age but is more common in children than in adults. Peak of onset usually occurs in the pre-school years and also in early adolescence, usually around the time of puberty. In children, trichotillomania affects boys and girls equally ...UVB phototherapy is delivered within a specially designed cabinet. Fluorescent light tubes are positioned to target affected areas with ultraviolet radiation (eg, hands or feet). For full body treatments, patients are undressed with genitalia covered, and eyes or full face should be protected with goggles or a face mask.Photosensitivity refers to various symptoms, diseases and conditions caused or aggravated by exposure to sunlight. A rash due to photosensitivity is a photodermatosis (plural photodermatoses). If the rash is eczematous, it is a photodermatitis. A chemical or drug that causes photosensitivity is a photosensitiser. DermNet now features a library of authentic patient cases with images. These cover the various symptoms, diagnosis, treatments, and outcomes that can be expected in the real world. You'll find these cases listed below. All of our content is written by medical professionals and reviewed by dermatologists before being published. Itchy anus is a common complaint described as an intense itch in the perianal area between the buttocks. Perianal itch can be the result of an infestation, skin infection, inflammatory skin condition, and, rarely, a skin tumour. When there is no obvious cause for the itch it is called pruritus ani.Dermatomyositis is thought to be caused by a microangiopathy affecting skin and muscle. There is a genetic predisposition to the development of dermatomyositis such as the PTPN22 gene and HLA associations identified include: Anti-Mi-2 antibodies: HLA DRB1*07 and DQA*0201. Silica exposure — in tradespeople. A melanocytic naevus (American spelling ‘ nevus ’), or mole, is a common benign skin lesion due to a local proliferation of pigment cells ( melanocytes ). It is sometimes called a naevocytic naevus or just 'naevus' (but note that there are other types of naevi ). A brown or black melanocytic naevus contains the pigment melanin, so may also ...

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Pityriasis rosea is a self-limiting rash, which resolves in about 6–10 weeks. It is characterised by a large circular or oval "herald patch", usually found on the chest, abdomen, or back. The herald patch is followed some time later, typically two weeks or so, by the development of smaller scaly oval red patches, resembling a Christmas tree ... A dermatofibroma can occur anywhere on the skin. Dermatofibroma size varies from 0.5–1.5 cm diameter; most lesions are 7–10 mm diameter. A dermatofibroma is tethered to the skin surface and mobile over subcutaneous tissue. The overlying skin dimples on pinching the lesion – the dimple or pinch sign. Colour may be pink to light brown in ...Chronic paronychia is a gradual process. It may start in one nail fold, particularly the proximal nail fold, but often spreads laterally and to several other fingers. Each affected nail fold is swollen and lifted off the nail plate. This allows the entry of organisms and irritants. The affected skin may be red and tender from time to time, and ... It may cause discomfort or bleeding when passing bowel motions, and aggravate any tendency to constipation, particularly in children. Lichen sclerosus causes adhesions and scarring. The clitoris may be buried. The labia minora resorb/shrink. The entrance to the vagina tightens (introital stenosis ). Sun damage ( photoageing, actinic keratoses) Repeated prior episodes of sunburn. Fair skin, blue eyes and blond or red hair — note; BCC can also affect darker skin types. Previous cutaneous injury, thermal burn, disease (eg cutaneous lupus, sebaceous naevus) Inherited syndromes: BCC is a particular problem for families with basal cell naevus ... What are the features of benign skin lesions? The features in common for benign skin lesions include: Symmetry in shape, colour and structure. Stable or slowly evolving. … A list of the most commonly used key terms and phrases in dermatology. What is seborrhoeic dermatitis? Seborrhoeic dermatitis is a common, chronic, or relapsing form of eczema /dermatitis that mainly affects the sebaceous gland -rich regions of the …Pseudofolliculitis barbae (PFB) is a common inflammatory reaction of the hair follicle, most often on the face as a result of shaving. Also known as “razor bumps” or “shaving bumps”, it can also occur on any site where hair is shaved or plucked, including the axilla, pubic area, and legs. Folliculitis barbae presents similarly, but is ...Melanoma of the nail unit is usually a variant of acral lentiginous melanoma, a malignant melanoma arising from the palms of the hands and soles of the feet. Other rare forms of melanoma that may arise in the nail unit are nodular melanoma or desmoplastic melanoma. Melanoma of the nail unit most often affects the great toe and thumbnail ... ….

Notalgia paraesthetica is a form of cutaneous dysaesthesia where itch and/or changed sensation arise in the areas of skin on the medial aspect of the shoulder blade on either side of the back. Notalgia means pain in the back, and paraesthetica refers to burning pain, tingling or itch. It is also called thoracic cutaneous nerve entrapment syndrome.Trachyonychia is characterised by brittle nails that show diffuse longitudinal ridging and can be accompanied by pitting, loss of lustre, or a roughened nail plate. Trachyonychia, also known as ‘rough nails’ or ‘sandpaper nails’, can involve any number of nails. Twenty-nail dystrophy refers to trachyonychia that affects all 20 nails.Carotenoderma is due to carotenaemia. Primary carotenaemia is usually due to excessive intake of carotenoid-containing foods or supplements. Carotene is found in all pigmented fruits and vegetables. High levels are associated with a deep yellow, orange, or green colour. Examples of fruit and vegetables with a high β-carotene content include ...A digital myxoid pseudocyst is a shiny papule found at the end of a finger or toe, close to the nail. It is called a pseudocyst because it is not surrounded by a capsule, unlike a true cyst. It is also called a myxoid cyst, a mucous cyst, a …Dermatitis herpetiformis (DH) is an inflammatoryimmunobullous disease of the skin and a cutaneousmanifestation of coeliac (celiac) disease, a gluten-sensitive enteropathy. The name herpetiformis is derived from the tendency for blisters to appear in clusters, resembling herpes simplex. However, DH is not due to viral infection.Carotenoderma is due to carotenaemia. Primary carotenaemia is usually due to excessive intake of carotenoid-containing foods or supplements. Carotene is found in all pigmented fruits and vegetables. High levels are associated with a deep yellow, orange, or green colour. Examples of fruit and vegetables with a high β-carotene content include ...UVB phototherapy is delivered within a specially designed cabinet. Fluorescent light tubes are positioned to target affected areas with ultraviolet radiation (eg, hands or feet). For full body treatments, patients are undressed with genitalia covered, and eyes or full face should be protected with goggles or a face mask.Trachyonychia is characterised by brittle nails that show diffuse longitudinal ridging and can be accompanied by pitting, loss of lustre, or a roughened nail plate. Trachyonychia, also known as ‘rough nails’ or ‘sandpaper nails’, can involve any number of nails. Twenty-nail dystrophy refers to trachyonychia that affects all 20 nails. Alopecia areata is an autoimmune condition affecting hair follicles causing hair loss. It typically presents with discrete bald patches on the scalp but can cause hair loss from all hair-bearing areas on the body. Alopecia is a Latin term meaning hair loss, and areata refers to the patchy nature of the hair loss. Nz dermnet, [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1], [text-1-1]